| Data | In casa | Ospite | Risultato |
|---|---|---|---|
| 13/09/25 16.30 | Ajax Amsterdam | PEC Zwolle | 3:1 |
| 13/09/25 18.45 | NEC Nijmwegen | PSV Eindhoven | 3:5 |
| 13/09/25 19.10 | Go Ahead Eagles Deventer | FC Volendam | 3:0 |
| 13/09/25 21.00 | FC Twente Enschede | NAC Breda | 2:2 |
| 13/09/25 21.00 | Feyenoord Rotterdam | SC Heerenveen | 1:0 |
| 14/09/25 12.15 | Excelsior Rotterdam | Sparta Rotterdam | 0:1 |
| 14/09/25 14.30 | Heracles Almelo | AZ Alkmaar | 1:2 |
| 14/09/25 14.30 | FC Utrecht | FC Groningen | 0:1 |
| 14/09/25 16.45 | Telstar | Fortuna Sittard | 1:3 |